Ayeza khan made her debut as a supporting actress. She first starred in drama Tum Jo Miley. She went on to perform some more supporting roles in dramas like Sandal, Pul Sirat and Larkiyan Mohallay Ki. Then came a breakthrough in her career when she did Tootay Huwey Per opposite Sami Khan. From there Ayeza established herself as a lead actress and stopped doing supporting roles. In some other of her hits Zard Mausam was also loved by the audience. She played the role of a troubled girl who suffers at the hands of her step mother and is confused in her relationships too. Another of her famous drama is Aks. She shared screen with well-established actresses like Nyla Jafferi and Saba Hameed and still proved her presence. She also starred in Kahi Unkahi opposite Shehryar Munawar Siddiqui. The pair was loved by the audience as they had not worked together before so they proved to be a breath of fresh air. Urwa Hocane played the antagonist in drama. People loved Ayeza and Shehryar’s couple which led to great success of the drama despite having a typical rich boy meets poor girl story. Adhoori Aurat also performed well on rating charts though Ayeza played a damsel in distress. Till then Ayeza has mostly played very innocent and crying roles. Then Ayeza changed the course of her career when she performed the role of a bold and out spoken girl in Pyare Afzal. She played the role of Farah Ibrahim who is the love interest of main protagonist played by Hamza Ali Abbasi. Pyare Afzal was the most popular and successful drama when it aired. Next she played two roles which were poles apart. She played the typical damsel in Mere Meherban and played a role on the happy side in Jab We Wed opposite Danish Taimoor. She also took a break in her career when everyone assumed that she was leaving showbiz industry but she came back with a bang and starred in Urdu1’s Tum Kon Piya opposite Imran Abbas Naqvi. She also starred in Shehernaz which was produced by her husband. She is currently working in two dramas which air on two big entertainment channels HUM TV and Geo Entertainment. One is Muhabbat Tum Se Nafrat Hai in which she plays lead opposite Imran Abbas and Shehzad sheikh. The other one is To Dil Ka Kya Hua in which she plays a very different role than her usual ones. She is working in the drama with Sami Khan after nearly three years. Previously they worked together in Do Qadam Dur Thay. Ayeza mostly does very eastern roles obviously with a few exceptions.