Eli Lilly and Co, an American pharmaceutical company, said on Thursday that fewer deaths were reported among COVID-19 patients taking a combination of its rheumatoid arthritis drug, ‘baricitinib’, and Gilead Sciences Inc’s ‘remdesivir’ in a clinical trial, compared to only remdesivir.
Lilly said the effect was most pronounced in patients on oxygen therapy, according to data from a U.S. government-backed trial, which however, was not designed to measure the effectiveness of in preventing death.
In-line with data disclosed in September, the combination helped shorten the median recovery time by one day compared to remdesivir alone, meeting the study’s main goal.
Lilly said 5.1% of patients on the drug combination died after 29 days versus 7.8% patients given remdesivir, which is already authorized in the U.S. for treating COVID-19 patients, and a placebo.
Baricitinib, licensed by Lilly from Incyte Corp and approved to treat rheumatoid arthritis in the United States, could help suppress a potentially lethal immune response to COVID-19 called “cytokine storm”.
Lilly said it was in talks with the U.S. Food and Drug Administration to gain emergency use authorization for treating COVID-19 patients.
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